Glycosyl compounds
Apexbio Technology LLC Sucralose 56038-13-2 10mM (in 1mL DMSO)
Sucralose (CAS 56038-13-2) is a synthetic chlorinated disaccharide widely employed as a noncaloric sweetener in biomedical and nutritional research It functions by binding to the sweet taste receptors (T1R2/T1R3) on the tongue eliciting a perceived sweetness substantially greater than that of sucrose Sucralose is minimally metabolized in the human body resulting in negligible caloric contribution and low systemic absorption Its metabolic stability and lack of glycemic impact make it a useful tool for investigating carbohydrate metabolism taste receptor signaling pathways and the physiological effects of nonnutritive sweeteners
Medchemexpress LLC VEGF-D Human CHO 10ug
VEGF-D Protein Human (CHO) is a regulator of both angiogenesis and lymphangiogenesis
Medchemexpress LLC Tarafenacin (D-tartrate) | 1159101-48-0 | 99.9% | 558.48 | 10 MM 1 ML
Tarafenacin (D-tartrate) is a highly selective M3 muscarinic receptor antagonist with a Ki of 0.19 nM. It demonstrates significant potency in inhibiting carbachol-induced bladder contractions without affecting atrial contractions, showing approximately 200-fold selectivity over the M2 receptor and high urinary versus cardiac selectivity. It also exhibits a much higher binding affinity to M5 mAChR compared to solifenacin.
- Highly selective M3 muscarinic receptor antagonist
- Ki of 0.19 nM
- Approximately 200-fold selectivity over M2 receptor
- Potent in inhibiting carbachol-induced bladder contractions
- High urinary versus cardiac selectivity (199-fold)
- Higher binding affinity to M5 mAChR than solifenacin
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL or greater
Chem-Impex International, Inc. Methyl-a-D-glucopyranoside | MFCD00064086 | 1KG
Methyl-a-D-glucopyranoside, MFCD00064086, 1KG
Medchemexpress LLC D-GsMTx4 | 99.4% | 4095.84 | 100 UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It acts as an inhibitor of the mechanosensitive ion channel Piezo2. It inhibits [Ca2+]i elevation and also impacts the mTOR and PI3K-Akt signaling pathways. D-GsMTx4 has been shown to inhibit mechanical allodynia and thermal hyperalgesia. It is suitable for research in areas such as mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Inhibits the mechanosensitive ion channel Piezo2.
- Inhibits [Ca2+]i elevation.
- Inhibits mTOR and PI3K-Akt signaling pathways.
- Inhibits mechanical allodynia and thermal hyperalgesia.
- Suitable for research on mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Decreases phosphorylation levels of proteins in the mTOR and PI3K-Akt signaling pathways in primary human lung fibroblasts.
Alkali Scientific Sucrose, ACS Grade, 10 Kg
Sucrose, ACS Grade, 10 Kg, is a high-purity, analytical grade chemical essential for laboratory applications requiring the highest standards of accuracy and reproducibility. It is commonly used in microbiological, biochemical, and pharmaceutical research, where it serves as a critical energy source for microbial cultures and as a substrate for enzymatic reactions. The 10 Kg size is designed for laboratories that need large quantities of sucrose for bulk media preparation, buffer solutions, and chemical assays. Its high purity ensures consistent results in advanced scientific research and industrial processes.
Alkali Scientific n Dodecyl β D maltoside, 25 G
n-Dodecyl Maltoside is a nonionic detergent commonly used for membrane protein solubilization. The 25g quantity provides ample material for large-scale protein extraction and solubilization applications. It is widely used in membrane protein research and proteomics due to its mild properties, which allow it to solubilize membrane proteins without denaturing them. This detergent is ideal for use in chromatography, electrophoresis, and structural analysis of membrane proteins. n-Dodecyl Maltoside is effective for maintaining protein functionality during solubilization, making it an essential tool for studies involving membrane-associated proteins in their native forms.
Medchemexpress LLC Deapioplatycodin D | 78763-58-3 | 1093.21 | 1 ML
Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, which exhibits anti-HCV (Hepatitis C Virus) activity. It is intended for research use only.
- HCV inhibitor
- Isolated from Platycodon grandiflorum
- Purity: 99.0%
- Exhibits antiproliferative activity against rat HSC-T6 cells (IC50: 8.24 μM)
Medchemexpress LLC TNF-alpha/TNFSF2 Mo 2ug
Recombinant mouse TNF-alpha/TNFSF2 protein (147 aa), corresponding to residues D89-L235 of mouse TNF-α, expressed in E. coli and supplied lyophilized. The product is >95% pure by reducing SDS-PAGE, has an apparent molecular weight of ~17.0 kDa, and is functionally validated in an L-929 cytotoxicity assay (ED50 = 1.616 pg/mL), making it suitable for signaling, bioactivity, and cytokine functional studies.
- Produced in E. coli for efficient bacterial expression.
- Purity greater than 95% by reducing SDS-PAGE.
- Corresponds to amino acids D89-L235 of mouse TNF-α (147 aa).
- Apparent molecular weight of approximately 17.0 kDa.
- Validated bioactivity in L-929 cytotoxicity assay (ED50 = 1.616 pg/mL).
- Supplied lyophilized for long-term storage and easy reconstitution.
Cayman Chemical n-DecylD-maltosIde 1g
A nonionic surfactant; commonly used to solubilize and stabilize membrane proteins; CMC = 1.8 mM; has been used in the expression of functional recombinant GPCRs
Chem-Impex International, Inc. 5-Bromo-4-chloro-3-indolyl-b-D-galactopyranoside | 7240-90-6 | MFCD00005666 | 5G
5-Bromo-4-chloro-3-indolyl-b-D-galactopyranoside, 7240-90-6, MFCD00005666, 5G